A new technique is introduced in order to solve the following question:When is a complete spacelike hypersurface of constant mean curvature in a generalized Robertson-Walker spacetime totally umbilical and a slice? (Generalized Robertson-Walker spacetimes extend classical Robertson-Walker ones to include the cases in which the fiber has not constant sectional curvature.) First, we determine when this hypersurface must be compact. Then, all these compact hypersurfaces in (necessarily spatially closed) spacetimes are shown to be totally umbilical and, except in very exceptional cases, slices. This leads to proof of a new Bernstein-type result. The power of the introduced tools is also shown by reproving and extending several known results.