Published in

BioMed Central, EPMA Journal, S1(5), 2014

DOI: 10.1186/1878-5085-5-s1-a15

BioMed Central, EPMA Journal, 1(1), p. 164-209, 2010

DOI: 10.1007/s13167-010-0001-x

Links

Tools

Export citation

Search in Google Scholar

Drug delivery systems: Advanced technologies potentially applicable in personalized treatments

Journal article published in 2010 by Jorge Fj Coelho, Paula C. Ferreira ORCID, Patricia Alves, Rosemeyre Cordeiro ORCID, Ana C. Fonseca, Joana R. Góis ORCID, Maria H. Gil
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Advanced drug delivery systems (DDS) present indubitable benefits for drug administration. Over the past three decades, new approaches have been suggested for the development of novel carriers for drug delivery. In this review, we describe general concepts and emerging research in this field based on multidisciplinary approaches aimed at creating personalized treatment for a broad range of highly prevalent diseases (e.g., cancer and diabetes). This review is composed of two parts. The first part provides an overview on currently available drug delivery technologies including a brief history on the development of these systems and some of the research strategies applied. The second part provides information about the most advanced drug delivery devices using stimuli-responsive polymers. Their synthesis using controlled-living radical polymerization strategy is described. In a near future it is predictable the appearance of new effective tailor-made DDS, resulting from knowledge of different interdisciplinary sciences, in a perspective of creating personalized medical solutions.