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American Academy of Neurology (AAN), Neurology, 12(64), p. 2132-2133, 2005

DOI: 10.1212/01.wnl.0000165977.38272.15

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"Applause sign" helps to discriminate PSP from FTD and PD

Journal article published in 2005 by B. Dubois, A. Slachevsky ORCID, B. Pillon, R. Beato, J. M. Villalponda, I. Litvan
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

The “applause sign” is a simple test of motor control that helps to differentiate PSP from frontal or striatofrontal degenerative diseases. It was found in 0/39 controls, 0 of 24 patients with frontotemporal dementia (FTD), 0 of 17 patients with Parkinson disease (PD), and 30/42 patients with progressive supranuclear palsy (PSP). It discriminated PSP from FTD (p < 0.001) and PD (p < 0.00). The “three clap test” correctly identified 81.8% of the patients in the comparison PSP and FTD and 75% of the patients in the comparison of PSP and PD.