Published in
American Society of Hematology, Blood, 8(126), p. 1005-1008, 2015
DOI: 10.1182/blood-2015-04-643361
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Recurrent CDKN1B (p27) mutations in hairy cell leukemia
Journal article published in 2015 by
Sascha Dietrich,
J. Hullein,
Jennifer Hüllein,
Stanley Chun-Wei Lee 
,
Barbara Hutter ,
David Gonzalez,
Sandrine Jayne,
Martin J. S. Dyer,
M. Ole,
Małgorzata Oleś,
Monica Else,
Xiyang Liu,
M. S abicki,
Mikołaj Słabicki ,
Bian Wu
and other authors.
,
Barbara Hutter ,
David Gonzalez,
Sandrine Jayne,
Martin J. S. Dyer,
M. Ole,
Małgorzata Oleś,
Monica Else,
Xiyang Liu,
M. S abicki,
Mikołaj Słabicki ,
Bian Wu
and other authors.
This paper is made freely available by the publisher.
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Abstract
Key Points Somatic CDKN1B (p27) mutations were identified in 16% (13/81) of HCL patients and coexist with BRAFV600E mutations. CDKN1B is the second most common mutated gene in HCL implicating altered cell cycle regulation and/or senescence in HCL.