Published in
American Society of Hematology, Blood, 15(125), p. 2435-2444, 2015
DOI: 10.1182/blood-2014-07-590232
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Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation
Journal article published in 2015 by
Antiopi Varelias,
Kate H. Gartlan 
,
Ellen Kreijveld,
Stuart D. Olver,
Mary Lor,
Rachel D. Kuns,
Katie E. Lineburg,
Bianca E. Teal,
Neil C. Raffelt,
Melody Cheong,
Kylie A. Alexander,
Motoko Koyama,
Kate A. Markey,
Elise Sturgeon,
Justine Leach
and other authors.
,
Ellen Kreijveld,
Stuart D. Olver,
Mary Lor,
Rachel D. Kuns,
Katie E. Lineburg,
Bianca E. Teal,
Neil C. Raffelt,
Melody Cheong,
Kylie A. Alexander,
Motoko Koyama,
Kate A. Markey,
Elise Sturgeon,
Justine Leach
and other authors.
This paper is made freely available by the publisher.
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Abstract
Key Points IL-6 is dysregulated after experimental allogeneic SCT and promotes alloantigen-dependent Th17 expansion within the lung. IL-6 is dysregulated in patients with IPS after clinical allogeneic SCT.