At the time of writing, million of patients worldwide are on a waiting list for a lifesaving organ transplant, 123,833 in the United States [1] and nearly 63,000 in the European Union [2]. However, the number of organs that become available each year falls far short of providing for those in need, and thousands die each year waiting for transplantation. There are clearly many missed opportunities in the severely brain-injured population, many patients dying without the care teams pursuing the chance to give life to others through donation [3, 4].Donation after brain death (BD) still remains the main source for organs, and it carries the advantage of being performed in a relatively controlled setting with ongoing perfusion and oxygenation. Death as determined by neurological criteria has been accepted worldwide [5, 6], and strict criteria exist for proper determination [7]. However, delays in the diagnosis of BD have been associated with decreased rates of organ donation, as well as dec ...