Published in
Elsevier, Leukemia Research, 6(12), p. 523-527, 1988
DOI: 10.1016/0145-2126(88)90120-8
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Amplification of c-myc and pvt-1 homologous sequences in acute nonlymphatic leukemia
Journal article published in 1988 by
Charlotte Asker,
Cristina Mareni,
Domenico Coviello 
,
Sigurdur Ingvarsson,
Mario Sessarego,
Paola Origone,
George Klein,
Janos Sumeigi
,
Sigurdur Ingvarsson,
Mario Sessarego,
Paola Origone,
George Klein,
Janos Sumeigi
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Abstract
Leukemic cells with double minute (DM) chromosomes from an ANLL(M1) patient were found to carry 10-15 fold amplified c-myc sequences. The linked pvt-1-like locus was amplified at the same level, suggesting that the c-myc amplicon is at least 300 kb in size.