Dissemin is shutting down on January 1st, 2025

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American Association for Cancer Research, Clinical Cancer Research, 9(21), p. 1978-1980, 2015

DOI: 10.1158/1078-0432.ccr-14-2604

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PLEKHA5: A Key to Unlock the Blood-Brain Barrier?

Journal article published in 2015 by Sylvia C. Eisele, Corey M. Gill ORCID, Ganesh M. Shankar, Priscilla K. Brastianos
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Brain metastases represent a devastating complication of melanoma. Our understanding of the mechanisms driving metastasis to the brain is limited. PLEKHA5 functions as a regulator of brain metastasis in melanoma, and further investigation is warranted to explore the use of PLEKHA5 as a potential therapeutic target. Clin Cancer Res; 21(9); 1978–80. ©2015 AACR. See related article by Jilaveanu et al., p. 2138