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American Society of Hematology, Blood, 5(117), p. 1444-1445, 2011

DOI: 10.1182/blood-2010-11-317198

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Activate Rac to rescue new vessels

Journal article published in 2011 by David D. Roberts ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Vascular endothelial growth factor (VEGF) is a major driver of physiologic and pathologic vascularization, but VEGF therapies generally fail to sustainably revascularize ischemic tissues. In this issue of Blood, Hoang and coworkers demonstrate that Rac1 may be the missing ingredient for achieving this goal.