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American Society for Microbiology, Journal of Clinical Microbiology, 2(51), p. 611-614, 2013

DOI: 10.1128/jcm.02279-12

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Rapid Whole-Genome Sequencing for Investigation of a Suspected Tuberculosis Outbreak

Journal article published in 2012 by M. Estée Török, M. Estée Török, Sandra Reuter, Josephine Bryant, Claudio U. Köser, Sian V. Stinchcombe, Bernadette Nazareth, Matthew J. Ellington, Stephen D. Bentley, Geoffrey P. Smith, Julian Parkhill ORCID, Sharon J. Peacock
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT Two Southeast Asian students attending the same school in the United Kingdom presented with pulmonary tuberculosis. An epidemiological investigation failed to link the two cases, and drug resistance profiles of the Mycobacterium tuberculosis isolates were discrepant. Whole-genome sequencing of the isolates found them to be genetically identical, suggesting a missed transmission event.