Published in
American Society of Hematology, Blood, 15(126), p. 1741-1752, 2015
DOI: 10.1182/blood-2015-05-644591
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- American Society of Hematology | PDF
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- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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IDH2 R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma
Journal article published in 2015 by
Chao Wang,
Timothy W. McKeithan,
Qiang Gong 
,
Weiwei Zhang,
Alyssa Bouska ,
Andreas Rosenwald,
Randy D. Gascoyne,
Xiwei Wu,
Jinhui Wang,
Zahid Muhammad,
Bei Jiang,
Joseph Rohr,
Andrew Cannon,
Christian Steidl,
Kai Fu
and other authors.
,
Weiwei Zhang,
Alyssa Bouska ,
Andreas Rosenwald,
Randy D. Gascoyne,
Xiwei Wu,
Jinhui Wang,
Zahid Muhammad,
Bei Jiang,
Joseph Rohr,
Andrew Cannon,
Christian Steidl,
Kai Fu
and other authors.
This paper is made freely available by the publisher.
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Abstract
Key Points IDH2 R172 mutations define a unique subgroup with distinct TFH-like gene expression signatures in AITL. IDH2 R172 mutations can induce DNA and repressive histone hypermethylation in AITL.