The aim of this work was to study the anticorrelation between ozone and UV-B radiation. The data were collected at the Southern Space Observatory (OES/CRSPE/INPE – MCT), located in the southern part of Brazil, and analyzed by linear and first order exponential fits. The UV-B radiation (280–315 nm) was measured by the UV-B radiometer (Eko Instruments – model MS-210W) and the total ozone column was measured by the Total Ozone Mapping Spectrometer (TOMS) installed on board of NASA's Earth Probe satellite. The UV-B radiation measurements employed for correlation analysis (from July 1999 to December 2001) had fixed solar zenith angles and were taken on days with clear sky. The mathematical behavior of correlations at different angles was observed and correlation coefficients were determined by linear and first order exponential fits. High correlation coefficient values were obtained for both fits studied and the differences between them can be considered small. The values for linear fits varied from R2=0.64 (SZA 55°) to 0.90 (SZA 30° and 35°) and for exponential fits varied from R2=0.63 (SZA 55°) to 0.85 (SZA 30° and 35°).