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Taylor and Francis Group, Nucleosides, Nucleotides and Nucleic Acids, 10-12(26), p. 1605-1609

DOI: 10.1080/15257770701548675

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A flexible method for the fabrication of gold nanostructures using oligonucleotide derivatives

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Several linear and branched DNA structures from 80-200 nm with a biotine molecule in the middle have been prepared. These structures have been decorated by addition of positively charged gold nanoparticles carrying 4-(dimethylamino)pyridine ligands. Streptavidin binds to the central biotine molecule introducing a 20 nm gap in the structure in which a biotinylated nanoparticle can be introduced. The simplest structure (80 nm, linear) is formed by 4 oligonucleotides. By changing some of these components changes on length, shape, and recognition system easily can be introduced.