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Medicina Oral S.L., Journal of Clinical and Experimental Dentistry, p. e197-202

DOI: 10.4317/jced.51420

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Pregabalin in the treatment of inferior alveolar nerve paraesthesia following overfilling of endodontic sealer

Journal article published in 2014 by Luis Oscar Alonso Ezpeleta, Pablo-J. Martín, José López López, Lizett Castellanos Cosano, Jenifer Martín González ORCID, Juan-J. Segura-Egea ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A case of orofacial pain and inferior alveolar nerve (IAN) paraesthesia after extrusion of endodontic sealer within the mandibular canal treated with prednisone and pregabalin is described. A 36-year-old woman underwent root canal treatment of the mandibular second right premolar tooth. Post-operative panoramic radiograph revealed the presence of radiopaque canal sealer in the mandibular canal. Damage to IAN consecutive to extrusion of endodontic sealer was diagnosed. Non-surgical management was decided, including: 1 mg/kg/day prednisone 2 times/day, once-daily regimen, and 150 mg/day pregabalin, two doses per day, monitoring the progress with periodic follow-up visits. Six weeks after the incident the signs and symptoms were gone. The complete resolution of paraesthesia and the control of pain achieved suggest that a non-surgical approach, combining prednisone and the GABA analogue pregabalin, is a good option in the management of the IAN damage subsequent to endodontic sealer extrusion.