Molecular hydropathicity index: Application to a series of allosteric modulators of the M 2 receptors
Journal article published in 1999 by
G. Vistoli 
,
A. Pedretti,
A. M. Villa,
L. Villa,
A. U. Holzgrabe,
A. Cambareri
,
A. Pedretti,
A. M. Villa,
L. Villa,
A. U. Holzgrabe,
A. Cambareri
This paper is made freely available by the publisher.
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Abstract
The hydropathicity of a series of compounds active as allosteric modulators at the M-2 muscarinic receptors was calculated and projected on the molecular surface. An analysis of the relationships between conformational and local hydropathicity properties was also performed.