Elsevier, Journal of Molecular Catalysis B: Enzymatic, 1-2(21), p. 3-8
DOI: 10.1016/s1381-1177(02)00136-4
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Rational engineering of enzyme properties has an enormous potential but is hampered by limitations in our understanding of the structural determinants of these properties. Recent examples of efforts in rational engineering illustrate the current state of the art.