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Oxford University Press, International Journal of Neuropsychopharmacology, 01(9), p. 131, 2005

DOI: 10.1017/s1461145705005559

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Serotonin transporter gene polymorphism (5-HTTLPR) and emotional response to auditory hallucinations in schizophrenia

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The serotonin transporter (5-HTT) has a crucial function in the regulation of serotonin (5-HT) reuptake in presynaptic neurons. 5-HT is a major modulator of emotional behaviour and circadian rhythms. In addition to its neurotransmitter role, it is also an important regulator of morphogenetic activities during early brain development as well as during adult neurogenesis and plasticity (Murphy et al., 2001).