Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

Hou, Liping; Heilbronner, Urs; Degenhardt, Franziska; Adli, Mazda; Akiyama, Kazufumi; Akula, Nirmala; Ardau, Raffaella; Arias, Bárbara; Backlund, Lena; Banzato, Claudio E. M.; Benabarre, Antoni; Bengesser, Susanne; Bhattacharjee, Abesh Kumar; Biernacka, Joanna M.; Birner, Armin; Brichant-Petitjean, Clara; Bui, Elise T.; Cervantes, Pablo; Chen, Guo-Bo; Chen, Hsi-Chung; Chillotti, Caterina; Cichon, Sven; Clark, Scott R.; Colom, Francesc; Cousins, David A.; Cruceanu, Cristiana; Czerski, Piotr M.; Dantas, Clarissa R.; Dayer, Alexandre; Étain, Bruno; Falkai, Peter; Forstner, Andreas J.; Frisén, Louise; Fullerton, Janice M.; Gard, Sébastien; Garnham, Julie S.; Goes, Fernando S.; Grof, Paul; Gruber, Oliver; Hashimoto, Ryota; Hauser, Joanna; Herms, Stefan; Hoffmann, Per; Hofmann, Andrea; Jamain, Stephane; Jiménez, Esther; Kahn, Jean-Pierre; Kassem, Layla; Kittel-Schneider, Sarah; Kliwicki, Sebastian; König, Barbara; Kusumi, Ichiro; Lackner, Nina; Laje, Gonzalo; Landén, Mikael; Lavebratt, Catharina; Leboyer, Marion; Leckband, Susan G.; Jaramillo, Carlos A. López; MacQueen, Glenda; Manchia, Mirko; Martinsson, Lina; Mattheisen, Manuel; McCarthy, Michael J.; McElroy, Susan L.; Mitjans, Marina; Mondimore, Francis M.; Monteleone, Palmiero; Nievergelt, Caroline M.; Nöthen, Markus M.; Ösby, Urban; Ozaki, Norio; Perlis, Roy H.; Pfennig, Andrea; Reich-Erkelenz, Daniela; Rouleau, Guy A.; Schofield, Peter R.; Schubert, K. Oliver; Schweizer, Barbara W.; Seemüller, Florian; Severino, Giovanni; Shekhtman, Tatyana; Shilling, Paul D.; Shimoda, Kazutaka; Simhandl, Christian; Slaney, Claire M.; Smoller, Jordan W.; Squassina, Alessio; Stamm, Thomas; Stopkova, Pavla; Tighe, Sarah K.; Tortorella, Alfonso; Turecki, Gustavo; Volkert, Julia; Witt, Stephanie; Wright, Adam; Young, L. Trevor; Zandi, Peter P.; Potash, James B.; DePaulo, J. Raymond; Depaulo,; Bauer, Michael; Reininghaus, Eva Z.; Novák, Tomas; Aubry, Jean-Michel; M., Maj; Maj, Mario; Baune, Bernhard T.; Mitchell, Philip B.; Vieta, Eduard; Frye, Mark A.; Rybakowski, Janusz K.; Kuo, Po-Hsiu; Kato, Tadafumi; Grigoroiu-Serbanescu, Maria; Reif, Andreas; Del Zompo, Maria; Bellivier, Frank; Schalling, Martin; Wray, Naomi R.; Kelsoe, John R.; Alda, Martin; Rietschel, Marcella; McMahon, Francis J.; Schulze, Thomas G.

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Urs Heilbronner
Hou et al., 2016

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Elsevier, The Lancet, 10023(387), p. 1085-1093, 2016

DOI: 10.1016/s0140-6736(16)00143-4

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@article{Hou2016,
  abstract = {Lithium is a first-line treatment in bipolar disorder, but individual response is variable. Previous studies have suggested that lithium response is a heritable trait. However, no genetic markers of treatment response have been reproducibly identified.},
  author = {Hou, Liping and Heilbronner, Urs and Degenhardt, Franziska and Adli, Mazda and Akiyama, Kazufumi and Akula, Nirmala and Ardau, Raffaella and Arias, Bárbara and Backlund, Lena and Banzato, Claudio E. M. and Benabarre, Antoni and Bengesser, Susanne and Bhattacharjee, Abesh Kumar and Biernacka, Joanna M. and Birner, Armin and Brichant-Petitjean, Clara and Bui, Elise T. and Cervantes, Pablo and Chen, Guo-Bo and Chen, Hsi-Chung and Chillotti, Caterina and Cichon, Sven and Clark, Scott R. and Colom, Francesc and Cousins, David A. and Cruceanu, Cristiana and Czerski, Piotr M. and Dantas, Clarissa R. and Dayer, Alexandre and Étain, Bruno and Falkai, Peter and Forstner, Andreas J. and Frisén, Louise and Fullerton, Janice M. and Gard, Sébastien and Garnham, Julie S. and Goes, Fernando S. and Grof, Paul and Gruber, Oliver and Hashimoto, Ryota and Hauser, Joanna and Herms, Stefan and Hoffmann, Per and Hofmann, Andrea and Jamain, Stephane and Jiménez, Esther and Kahn, Jean-Pierre and Kassem, Layla and Kittel-Schneider, Sarah and Kliwicki, Sebastian and König, Barbara and Kusumi, Ichiro and Lackner, Nina and Laje, Gonzalo and Landén, Mikael and Lavebratt, Catharina and Leboyer, Marion and Leckband, Susan G. and Jaramillo, Carlos A. López and MacQueen, Glenda and Manchia, Mirko and Martinsson, Lina and Mattheisen, Manuel and McCarthy, Michael J. and McElroy, Susan L. and Mitjans, Marina and Mondimore, Francis M. and Monteleone, Palmiero and Nievergelt, Caroline M. and Nöthen, Markus M. and Ösby, Urban and Ozaki, Norio and Perlis, Roy H. and Pfennig, Andrea and Reich-Erkelenz, Daniela and Rouleau, Guy A. and Schofield, Peter R. and Schubert, K. Oliver and Schweizer, Barbara W. and Seemüller, Florian and Severino, Giovanni and Shekhtman, Tatyana and Shilling, Paul D. and Shimoda, Kazutaka and Simhandl, Christian and Slaney, Claire M. and Smoller, Jordan W. and Squassina, Alessio and Stamm, Thomas and Stopkova, Pavla and Tighe, Sarah K. and Tortorella, Alfonso and Turecki, Gustavo and Volkert, Julia and Witt, Stephanie and Wright, Adam and Young, L. Trevor and Zandi, Peter P. and Potash, James B. and DePaulo, J. Raymond and Depaulo,  and Bauer, Michael and Reininghaus, Eva Z. and Novák, Tomas and Aubry, Jean-Michel and M., Maj and Maj, Mario and Baune, Bernhard T. and Mitchell, Philip B. and Vieta, Eduard and Frye, Mark A. and Rybakowski, Janusz K. and Kuo, Po-Hsiu and Kato, Tadafumi and Grigoroiu-Serbanescu, Maria and Reif, Andreas and Del Zompo, Maria and Bellivier, Frank and Schalling, Martin and Wray, Naomi R. and Kelsoe, John R. and Alda, Martin and Rietschel, Marcella and McMahon, Francis J. and Schulze, Thomas G.},
  doi = {10.1016/s0140-6736(16)00143-4},
  journal = {The Lancet},
  month = {jan},
  pages = {1085-1093},
  title = {Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study},
  url = {https://dash.harvard.edu/bitstream/handle/1/32072234/4814312.pdf?sequence=1},
  volume = {387},
  year = {2016}
}

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