Published in

Elsevier, Alzheimer's && Dementia :: Diagnosis, Assessment && Disease Monitoring, 1(2), p. 19-26, 2015

DOI: 10.1016/j.dadm.2015.11.003

Links

Tools

Export citation

Search in Google Scholar

Sensitivity of composite scores to amyloid burden in preclinical Alzheimer's disease: Introducing the Z-scores of Attention, Verbal fluency, and Episodic memory for Nondemented older adults composite score

Journal article published in 2015 by Lim Yy, Villemagne Vl, Yen Ying Lim, Peter J. Snyder, Snyder Pj, Robert H. Pietrzak, Pietrzak Rh, Albulene Ukiqi, Victor L. Villemagne, David Ames, Olivier Salvado, Pierrick Bourgeat ORCID, Martins Rn, Ralph N. Martins ORCID, Masters Cl and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Red circle
Postprint: archiving forbidden
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

Cognitive composite scores developed for preclinical Alzheimer's disease (AD) often consist of multiple cognitive domains as they may provide greater sensitivity to detect β-amyloid (Aβ)–related cognitive decline than episodic memory (EM) composite scores alone. However, this has never been empirically tested. We compared the rate of cognitive decline associated with high Aβ (Aβ+) and very high Aβ (Aβ++) in cognitively normal (CN) older adults on three multidomain cognitive composite scores and one single-domain (EM) composite score.