Published in

BioMed Central, Arthritis Research and Therapy, 1(18), 2016

DOI: 10.1186/s13075-015-0912-y

Links

Tools

Export citation

Search in Google Scholar

Two-year results of disease activity score (DAS)-remission-steered treatment strategies aiming at drug-free remission in early arthritis patients (the IMPROVED-study)

Journal article published in 2016 by Lotte Heimans, Gülşah Akdemir ORCID, Kirsten V. C. Wevers-De Boer, Kirsten V. C. Wevers de Boer, Yvonne P. Goekoop Ruiterman, Esmeralda T. Molenaar, Johannes H. L. M. van Groenendael, Andreas J. Peeters, Gerda M. Steup Beekman, Leroy R. Lard, Peter B. J. de Sonnaville, Bernard A. M. Grillet, Tom W. J. Huizinga, Cornelia F. Allaart
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Abstract Background Early suppression of disease activity in (rheumatoid) arthritis (RA) patients may result in drug-free remission and prevent damage. We assessed 2-year clinical and radiological outcomes of two disease activity score (DAS)-remission-steered treatment strategies in early arthritis patients. Methods Patients (n = 610) with early RA or undifferentiated arthritis (UA) were treated with methotrexate (MTX) and tapered high dose of prednisone. Patients in early remission (44/53 joints DAS