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Published in

American Society for Microbiology, Journal of Clinical Microbiology, 10(39), p. 3700-3702, 2001

DOI: 10.1128/jcm.39.10.3700-3702.2001

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Rapid Detection of Methicillin Resistance in Coagulase-Negative Staphylococci by a Penicillin-Binding Protein 2a-Specific Latex Agglutination Test

Journal article published in 2001 by M. A. Horstkotte, Horstkotte Ma, Knobloch Jk, Jkm K.-M. Knobloch ORCID, H. Rohde ORCID, D. Mack
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT The detection of PBP 2a by the MRSA-Screen latex agglutination test with 201 clinical coagulase-negative staphylococci had an initial sensitivity of 98% and a high degree of specificity for Staphylococcus epidermidis strains compared to PCR for mecA . Determination of oxacillin MICs evaluated according to the new breakpoint (0.5 μg/ml) of the National Committee for Clinical Laboratory Standards exhibited an extremely low specificity for this population.