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Elsevier, Cell Stem Cell, 4(14), p. 417-418, 2014

DOI: 10.1016/j.stem.2014.03.007

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How Tets and Cytoskeleton Dynamics MET in Reprogramming

Journal article published in 2014 by Laurent David ORCID, Calley L. Hirsch
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Two studies by Sakurai et al. (2014) and Hu et al. (2014) in this issue of Cell Stem Cell add a new level of understanding to the mesenchymal-to-epithelial transition taking place during reprogramming, showing how this morphological transformation is promoted by Tet enzymes and blocked by kinase-dependent cytoskeletal organization.