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Sociedade Brasileira de Microbiologia, Brazilian Journal of Microbiology, 3(40), p. 535-540

DOI: 10.1590/s1517-83822009000300015

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Determination of the antibacterial activity of crude extracts and compounds isolated from Hortia oreadica (Rutaceae) against oral pathogens

Journal article published in 2009 by Vanessa Gisele Pasqualotto Severino, Maria Fátima das Graças Fernandes da Silva, Adriana Helena Chicharo Vinholis, Maria Fátima das Graças Fernandes D. Silva, Rodrigo Lucarini, Lilian Bueno Montanari, Wilson Roberto Cunha ORCID, Adriana Helena Chicharo Vinholis, Carlos Henrique Gomes Martins, Carlos Henrique Gomes Martins
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Extracts from Hortia oreadica afforded four dihydrocinnamic acid derivatives, isolated from the n-hexane extract, as well as limonoid guyanin and the furoquinoline alkaloid dictamnine, both isolated from the dichloromethane extract. The extracts and the isolated compounds were tested against some oral pathogens, so as to investigate their antibacterial activity. The results showed that the n-hexane extract and the compound dictamnine are the most active against the selected microorganisms.