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American Chemical Society, Langmuir, 5(24), p. 1613-1616, 2008

DOI: 10.1021/la703235y

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Length-Based Encoding of Binary Data in DNA

Journal article published in 2008 by Nathaniel G. Portney, Yonghui Wu, Lauren K. Quezada ORCID, Stefano Lonardi, Mihrimah Ozkan
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We developed a system to encode digital information in DNA polymers based on the partial restriction digest (PRD). Our encoding method relies on the length of the fragments obtained by the PRD rather than the actual content of the nucleotide sequence, thus eliminating the need for expensive sequencing machinery. In this letter, we report on the encoding of 12 bits of data in a DNA fragment of 110 nucleotides and the process of recovering the data.