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Elsevier, Journal of Advanced Research, 3(6), p. 319-330, 2015

DOI: 10.1016/j.jare.2014.11.012

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Mesothelioma treatment: Are we on target? A review

Journal article published in 2015 by Birgitta I. Hiddinga, Christian Rolfo, Jan P. van Meerbeeck ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Targeted treatment is a therapy directed at a specific molecular target close to a hallmark of cancer. The target should be measurable with a biomarker and measurement of the target should correlate with clinical outcome when targeted treatment is administered. Current clinical guidelines do not recommend targeted or biological therapy in MPM. However, since these recommendations came out, new agents have been investigated in MPM. This review updates the use of targeted and biological treatment in patients with mesothelioma.