A graph is said to be vertex-transitive if its automorphism group acts transitively on the vertex set. Some recent developments and possible future directions regarding two famous open problems, asking about existence of Hamilton paths and existence of semiregular au-tomorphisms in vertex-transitive graphs, are discussed, together with some recent results on arc-transitive graphs and half-arc-transitive graphs, two special classes of vertex-transitive graphs that have received particular attention over the last decade.