Crude plant extracts, their fractios and purified compounds are reported as natural antimicrobial agents and/or antioxidant substances. Here we report the antibacterial and phagocyte modulant activity of A. chinensis leaf fractions. The aqueous extract fron these leaves was dried and progressively extracted in different solvents (chloroform, ethyl, acetate). These extracts were tested for their antibacterial activity on Gram-positive and Gram-negative bacterial strains, using a broth dilution test. A luminol-dependent chemiluminescence (CL) assay wasused to study their activity on human whole blood leukocytes. The ethyl acetate fraction had a strong antimicrobial effect on all bacterial strains and showed a significant antioxidant activity on phagocytes, inhibiting the respiratory burst measured by CL. This Actinidia leaf fraction, analyzed by HPLC, was rich in flavonoids such as rutin, esperidin, quercetin, apigenin and canferol in addition to the well known content of ascorbic acid. As all these compounds have anti-oxidant, antimicrobial, anti-infiammatory and other effects on eukaryotic cells as well as allelopathic activity in plants, the A. chinensis leaves can be important in medicine and agriculture.