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MDPI, Marine Drugs, 6(12), p. 3608-3633, 2014

DOI: 10.3390/md12063608

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Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium

Journal article published in 2014 by Camila Spereta Bertanha, Ana Helena Januário ORCID, Tavane Aparecida Alvarenga, Letícia Pereira Pimenta, Márcio Luis Andrade E. Silva, Wilson Roberto Cunha ORCID, Patrícia Mendonça Pauletti
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucidation, and biological activities of quinones, hydroquinones, rossinones, longithorones, longithorols, floresolides, scabellones, conicaquinones, aplidinones, thiaplidiaquinones, and conithiaquinones. A compilation of the 13C-NMR spectral data of these compounds is also presented.