Published in
American Society of Hematology, Blood, 14(125), p. 2245-2253, 2015
DOI: 10.1182/blood-2014-05-575001
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Morgana acts as an oncosuppressor in chronic myeloid leukemia
Journal article published in 2015 by
Augusta Di Savino,
Cristina Panuzzo,
Stefania Rocca,
Ubaldo Familiari,
Rocco Piazza,
Sabrina Crivellaro,
Giovanna Carrà 
,
Roberta Ferretti,
Federica Fusella,
Emilia Giugliano,
Annalisa Camporeale,
Irene Franco,
Barbara Miniscalco,
Juan Carlos Cutrin,
Emilia Turco
and other authors.
,
Roberta Ferretti,
Federica Fusella,
Emilia Giugliano,
Annalisa Camporeale,
Irene Franco,
Barbara Miniscalco,
Juan Carlos Cutrin,
Emilia Turco
and other authors.
This paper is made freely available by the publisher.
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Abstract
Key Points Morgana haploinsufficiency in mice causes a lethal and transplantable CML-like myeloid neoplasm. Morgana is underexpressed in aCML and in a subgroup of CMLs, where it predicts a worse response to imatinib but sensitivity to ROCK inhibitors.