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Centers for Disease Control and Prevention, Emerging Infectious Diseases, 12(21), p. 2225-2229, 2015

DOI: 10.3201/eid2112.150132

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Sindbis and Middelburg Old World Alphaviruses Associated with Neurologic Disease in Horses, South Africa

Journal article published in 2015 by Stephanie Van Niekerk, Stacey Human ORCID, June Williams, Erna van Wilpe, Marthi Pretorius ORCID, Robert Swanepoel, Marietjie Venter
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Old World alphaviruses were identified in 52 of 623 horses with febrile or neurologic disease in South Africa. Five of 8 Sindbis virus infections were mild; 2 of 3 fatal cases involved co-infections. Of 44 Middelburg virus infections, 28 caused neurologic disease; 12 were fatal. Middelburg virus likely has zoonotic potential.