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Royal Society of Chemistry, RSC Advances, 45(5), p. 35412-35420, 2015

DOI: 10.1039/c5ra04968g

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Experimental and theoretical evaluation of trans-3-halo-2-hydroxy-tetrahydropyran conformational preferences. Beyond anomeric interaction

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Which analysis will explain the preferences of the substituents in the hydro-halo-tetrahydropyran rings? Is the anomeric effect essential to understand what is going on?