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Royal Society of Chemistry, RSC Advances, 48(5), p. 38271-38276, 2015

DOI: 10.1039/c5ra02975a

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Enzyme-catalysed regio- and enantioselective preparative scale synthesis of (S)-2-hydroxy alkanones

Journal article published in 2015 by Christoph Loderer ORCID, M. B. Ansorge-Schumacher
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The alcohol dehydrogenase CPCR2 was applied for the asymmetric reduction of 2,3-alkanediones to the corresponding (S)-2-hydroxy alkanones with high regio- and stereoselectivity and in preparative scale.