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American Society for Microbiology, Journal of Clinical Microbiology, 3(54), p. 802-804, 2016

DOI: 10.1128/jcm.03002-15

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Flow Cytometry To Assess Cerebrospinal Fluid Fungal Burden in Cryptococcal Meningitis

Journal article published in 2015 by James E. Scriven ORCID, Lisa M. Graham, Charlotte Schutz, Thomas J. Scriba, Robert J. Wilkinson ORCID, David R. Boulware, Graeme Meintjes, David G. Lalloo, Britta C. Urban
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT Fungal burden in the cerebrospinal fluid is an important determinant of mortality in cryptococcal meningitis, but its use in aiding clinical decision making is hampered by the time involved to perform quantitative cultures. Here, we demonstrate the potential of flow cytometry as a novel and rapid technique to address this issue.