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Nature Research, Nature Reviews Clinical Oncology, 8(12), p. 439-440, 2015

DOI: 10.1038/nrclinonc.2015.118

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Combined immunotherapy—a new standard in metastatic melanoma?

Journal article published in 2015 by Axel Hauschild, Claus Garbe ORCID
This paper was not found in any repository; the policy of its publisher is unknown or unclear.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.

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Abstract

The efficacy of immunotherapy in metastatic melanoma is established, with anti-CTLA-4 and anti-PD-1 antibody-based therapies providing unexpectedly high responses and prolonged survival. The combination of nivolumab and ipilimumab is now poised to become the new standard of care, based on a 61% response rate in a recent randomized extended phase I/II trial, confirmed by phase III data presented at ASCO 2015.