Abstract This paper provides an account of the performance of an experimental version of the Hurricane Weather Research and Forecasting system (HWRFX) for 87 cases of Atlantic tropical cyclones during the 2005, 2007, and 2009 hurricane seasons. The HWRFX system was used to study the influence of model grid resolution, initial conditions, and physics. For each case, the model was run to produce 126 h of forecast with two versions of horizontal resolution, namely, (i) a parent domain at a resolution of about 27 km with a 9-km moving nest (27:9) and (ii) a parent domain at a resolution of 9 km with a 3-km moving nest (9:3). The former was selected to be consistent with the current operational resolution, while the latter is the first step in testing the impact of finer resolutions for future versions of the operational model. The two configurations were run with initial conditions for tropical cyclones obtained from the operational Geophysical Fluid Dynamics Laboratory (GFDL) and HWRF models. Sensitivity experiments were also conducted with the physical parameterization scheme. The study shows that the 9:3 HWRFX system using the GFDL initial conditions and a system of physics similar to the operational version (HWRF) provides the best results in terms of both track and intensity prediction. Use of the HWRF initial conditions in the HWRFX model provides reasonable skill, particularly when used in cases with initially strong storms (hurricane strength). However, initially weak storms (below hurricane strength) posed special challenges for the models. For the weaker storm cases, none of the predictions from the HWRFX runs or the operational GFDL forecasts provided any consistent improvement when compared to the operational Statistical Hurricane Intensity Prediction Scheme with an inland decay component (DSHIPS).