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Elsevier, Bioorganic and Medicinal Chemistry Letters, 16(13), p. 2683-2686

DOI: 10.1016/s0960-894x(03)00537-7

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Oxime bond formation for the covalent attachment of oligonucleotides on glass support

Journal article published in 2003 by Eric Defrancq ORCID, Antoine Hoang, Françoise Vinet, Pascal Dumy ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The chemical attachment of oligonucleotides on glass slides has been achieved using oxime bond formation. This method has been shown very efficient by comparison with the attachment of amino-oligonucleotides via reductive amination.