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Elsevier, Data in Brief, (6), p. 405-409, 2016

DOI: 10.1016/j.dib.2015.12.025

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Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress

Journal article published in 2016 by Ravirajsinh N. Jadeja ORCID, Nathalie H. Urrunaga, Daniel Ahmad, Sandeep Khurana
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We recently demonstrated the role of M1 muscarinic receptors (M1R) in modulating oxidative stress in liver and hepatocytes (Urrunaga et al., 2015) [1]. Here we provide data regarding the effect of a novel M1R agonist, VU0357017 (Lebois et al., 2010) [2], on H2O2-mediated hepatocyte injury, the effect of an M1R antagonist VU0255035 (Sheffler et al., 2009) [3] on catalase and super oxide dismutase (SOD) activities in H2O2–treated hepatocytes in vitro, and finally, the effect of M1R ablation on hepatic catalase activity in acetaminophen (APAP)-treated mice.