The Trecastagni Fault is a NNW–SSE tectonic structure in the densely inhabited southern flank of Mt. Etna, characterised by evident morphological scarps and movements of normal and right-lateral type that directly af-fect roads and buildings. The fault is affected by continuous dynamics with intermittent accelerations accompa-nied with shallow seismicity. It has an important role in the instability affecting Mt. Etna's south-eastern flank and represents part of the southern boundary of the unstable sector. The motion of the fault between 2005 and 2011 has been analysed by using a multi-disciplinary approach involving terrestrial and satellite ground de-formation data. Active monitoring systems able to investigate the fault in detail are extensometers, a levelling network and InSAR. Two episodes of acceleration were recorded at the end of 2009 and during 2010. Data evi-dences that the acceleration episodes affected only portions of the fault and that stress may accumulate and be periodically released. Although both magmatic processes (inflation or intrusive episodes) and flank dynamics influence the occurrence of the TF acceleration episodes, the dragging effect of the overall seaward sliding of the south-eastern flank is evident and it causes the subsidence of the hangingwall, accumulating stress on the fault that is periodically seismically released.