Published in

Wiley-VCH Verlag, ChemInform, 13(35), 2004

DOI: 10.1002/chin.200413114

Elsevier, Bioorganic and Medicinal Chemistry Letters, 24(13), p. 4365-4369

DOI: 10.1016/j.bmcl.2003.08.080

Links

Tools

Export citation

Search in Google Scholar

Substituted azoloquinolines and -quinazolines as new potent farnesyl protein transferase inhibitors

Journal article published in 2003 by et A.-L. et A.-L., Patrick Angibaud, Xavier Bourdrez, David W. End, Eddy Freyne, Michel Janicot, Patricia Lezouret, Yannick Ligny, Geert Mannens, Siegrid Damsch, Laurence Mevellec, Christophe Meyer ORCID, Philippe Muller, Isabelle Pilatte, Virginie Poncelet and other authors.
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Red circle
Preprint: archiving forbidden
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

A series of (4-chlorophenyl)-alpha-(1-methyl-1H-imidazol-5-yl)azoloquinolines and -quinazolines was prepared. These compounds displayed potent Farnesyl Protein Transferase inhibitory activity and tetrazolo[1,5-a]quinazolines are promising agents for oral in vivo inhibition.