Cell Press, Neuron, 4(37), p. 549-550, 2003
DOI: 10.1016/s0896-6273(03)00087-4
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In this issue of Neuron, Saal et al. find that exposure to any of five addictive drugs or exposure to a brief stressor produces a shared cellular modification of excitatory synapses in the ventral tegmental area (VTA). This common response may represent a starting point for dissecting early changes that underlie addiction.