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Elsevier, Tetrahedron, 43(67), p. 8392-8403

DOI: 10.1016/j.tet.2011.08.001

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Nitrogen-Bridged Heterocycles via Cycloaddition of Non-classical Heterocyclic-Fused-[c]thiazoles.

Journal article published in 2011 by Maria I. L. Soares ORCID, Clara S. B. Gomes, Teresa M. V. D. Pinho e. Melo ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

a b s t r a c t The [4pþ2p] cycloaddition of non-classical heterocyclic-fused-[c]thiazoles was explored allowing the synthesis of a range of new nitrogen-bridged bi-, tri-and tetracyclic heterocyclic compounds namely, pyrazolo[1,5-a]pyridines, thiazolo[2,3,4-cd]pyrrolizines and indolizines. For the first time, one non-classical pyrrolo[1,2-c]thiazole was isolated and its structure determined by X-ray crystallography.