Elsevier, Mechanisms of Development, 1-2(87), p. 203-206, 1999
DOI: 10.1016/s0925-4773(99)00149-5
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We have cloned c-Irx2, a chick homologue of the Xiro2 and mIrx2 genes and a new member of the Iroquois family of homeodomain-containing transcription factors. Strikingly, c-Irx2 expression reveals an early subdivision of the neural plate at late primitive streak stages which later transiently resolves to a single stripe within the developing hindbrain corresponding to rhombomere 1.