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Elsevier, Clinical Neurophysiology, 9(123), p. 1736-1744, 2012

DOI: 10.1016/j.clinph.2012.02.062

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In vivo neuronal firing patterns during human epileptiform discharges replicated by electrical stimulation

Journal article published in 2012 by Gonzalo Alarcón, Sv Kerai, Me Lacruz, Juan Martinez, Quiroga Rq, Rodrigo Quian Quiroga ORCID, Selway Rp, Richard P. Selway, Mark P. Richardson, García Seoane Jj, Richardson Mp, Jorge J. García Seoane, Antonio Valentín ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

► The neuronal firing patterns during interictal epileptiform discharges (IEDs) and after single pulse electrical stimulation (SPES) can be described as burst-only, suppression-only, burst–suppression or no-change. ► Similar neuronal firing patterns can be observed during IEDs and after SPES. ► IEDs and responses to SPES appear to activate similar and generic cortical mechanisms, which may explain transient cognitive impairment.