Graphical Abstract Highlights d Membrane IgE appears transiently and is then internalized d The IgE B cell receptor (BCR) spontaneously co-localizes with lipid rafts d IgE BCR expression restrains mobility responses to chemokines d mIgE promotes apoptosis of IgE + cells, severely impacting their fate Correspondence cogne@unilim.fr In Brief IgE responses may convey severe allergy and thus need tight control. Laffleur et al. demonstrate a self-restrained B cell stage where membrane IgE expression impacts the phenotype, shape, and mobility of B lymphocytes, promotes apoptosis, and severely shortens IgE + B cell fate.