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Wiley, Chinese Journal of Chemistry, 4(30), p. 959-964, 2012

DOI: 10.1002/cjoc.201100206

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A Rapid Access to Novel and Known Benzimidazole Derivatives Using Silica Chloride as a Reusable Catalyst

Journal article published in 2012 by Bahador Karami, Vahideh Ghashghaee, Saeed Khodabakhshi ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

A new application of silica chloride as an easily available and reusable solid acid catalyst for the synthesis of benzimidazole and its derivatives through the condensation of o-phenylenediamines and orthoesters under thermal and solvent-free conditions is described. This novel and eco-friendly method is very cheap and has many advantages including excellent yields, short reaction time, and simple work-up procedure. Copyright © 2012 SIOC, CAS, Shanghai & WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.