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Oxford University Press, Nucleic Acids Research, 1(29), p. 44-48, 2001

DOI: 10.1093/nar/29.1.44

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Proteome Analysis Database: online application of InterPro and CluSTr for the functional classification of proteins in whole genomes

Journal article published in 2001 by Margaret Biswas, Wolfgang Fleischmann, Er Kanapin, Youla Karavidopoulou ORCID, Paul Kersey, Evgenia V. Kriventseva, Virginie Mittard, Nicola Mulder, Isabelle Phan, Evgeni Zdobnov, Rolf Apweiler
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The SWISS-PROT group at EBI has developed the Proteome Analysis Database utilising existing resources and providing comparative analysis of the predicted protein coding sequences of the complete genomes of bacteria, archaea and eukaryotes (http:// www.ebi.ac.uk/proteome/). The two main projects used, InterPro and CluSTr, give a new perspective on families, domains and sites and cover 31--67% (InterPro statistics) of the proteins from each of the complete genomes. CluSTr covers the three complete eukaryotic genomes and the incomplete human genome data. The Proteome Analysis Database is accompanied by a program that has been designed to carry out InterPro proteome comparisons for any one proteome against any other one or more of the proteomes in the database.