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Elsevier, Transplantation Proceedings, 7(44), p. 1953-1955

DOI: 10.1016/j.transproceed.2012.06.020

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Stages of Early Acute Renal Dysfunction in Liver Transplantation: The Influence of Graft Function

Journal article published in 2012 by Ilaria Umbro, Massimo Rossi, Francesca Tinti, F. Fiacco, P. Piselli ORCID, S. Ianni, Stefano Ginanni Corradini, S. Ginanni Corradini ORCID, Luca Poli, Pasquale Bartolomeo Berloco, Anna Paola Mitterhofer
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Abstract

The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function. © 2012 Published by Elsevier Inc.