New corrole–D-galactose conjugates were synthesized from the reaction of 5,10,15-tris(pentafluorophe-nyl)corrole and 1,2:3,4-di-O-isopropylidene-a-D-galactopyranose. The monosubstituted isomers were fully characterized by NMR spectroscopy and mass spectrometry. The latter studies can be used to differ-entiate the two conjugate isomers. The photophysical properties and the photodynamic effect on Jurkat cells were evaluated for the main conjugate isolated.