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Wiley-VCH Verlag, ChemInform, 40(31), p. no-no, 2000

DOI: 10.1002/chin.200040218

Elsevier, Bioorganic and Medicinal Chemistry Letters, 11(10), p. 1265-1267

DOI: 10.1016/s0960-894x(00)00201-8

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The synthesis and in vitro cytotoxic studies of novel oxa-spermidine derivatives and homologues

Journal article published in 2000 by Vladimir A. Kuksa, Valentin A. Pavlov ORCID, Paul Kong Thoo Lin, Paul Kong Thoo Lin
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

A series of oxa-spermidine derivatives and homologues were prepared and their anticancer properties were evaluated. All these compounds showed an average GI50 value in the range of 3.9-28.9 microM. SAR studies showed that the presence of a sulphonamido functionality and the length of the alkyl chain are important factors for an enhanced activity.