Published in
Elsevier, Tetrahedron, 5(70), p. 1077-1083, 2014
DOI: 10.1016/j.tet.2013.12.026
Links
Tools
New Tetracyclic 1,4-Oxazepines Constructed via Practically Simple Tandem Condensation Strategy from Readily Available Synthons
Journal article published in 2013 by
Alexander V. Sapegin,
Stanislav A. Kalinin,
Alexey V. Smirnov,
Mikhail V. Dorogov,
Mikhail Krasavin 
This paper is available in a repository.
Full text: Download
Published version:
archiving forbidden
Data provided by 
Abstract
A streamlined synthetic methodology towards novel tetracyclic 1,4-oxazepines from readily available precursors is described. The compounds, designed as more soluble version of the earlier described, poorly soluble dibenzo[b,f][1,4]oxazepines, were obtained in high yields and as a single regioisomer as a result of three tandem chemical events—nucleophilic aromatic substitution, Smiles rearrangement and denitrocyclization.